For clinics & practitioners

Offer clinically studied probiotics in your practice

MIOME is built on two clinically studied strains, Bacillus coagulans Unique IS-2™ (MTCC 5260) and Bacillus coagulans LactoSpore® (MTCC 5856), to support occasional constipation, bloating, and digestive upset.

Recommend it to your patients with no inventory, stock it in your clinic at wholesale, or do both.

Our clinical evidence hub is password-protected. If your password hasn't been emailed to you, request your password here.

For US clinics and practitioners. By application.
Taking a MIOME IB-ONE capsule with a glass of water
Why MIOME

Probiotics you can recommend with confidence

The strain is the evidence

Probiotic effects are strain-specific. MIOME uses defined Bacillus coagulans strains backed by published human clinical studies, each delivered at the dose used in those studies, not a generic high-CFU blend.

Made for the clinic conversation

A simple once-a-day capsule and plain-language patient materials you can share. The product is built to support the recommendation you make.

Quality you can stand behind

Third-party tested for purity, low FODMAP, and free from gluten, dairy, and soy. Shelf-stable with a long shelf life, so there's no refrigeration to manage in the clinic.

The evidence

Built on strain-specific science

Across the two strains, MIOME draws on more than 10 human clinical studies in digestive health, including multiple randomized, double-blind, placebo-controlled studies, each delivered at the dose used in the published research. The full strain-by-strain detail lives in our clinical evidence hub.

10+
Human clinical studies on digestive health, across the two strains
Studied doses
Each strain delivered at the amount used in its studies
Third-party tested
For purity, heavy metals, and microbiological quality
AEProbio
IB-ONE is listed in the 2026 Clinical Guide to probiotics in the USA
Bacillus coagulans Unique IS-2™(MTCC 5260) · in IB-ONE and IB-PRO
Studied in constipation over 4 weeks.
Constipation: bowel movements per week
A step change, not a slow climb.
0246Bowel movements / weekwk 1wk 2wk 3wk 4Weeks of daily use11.74.26

Spontaneous bowel movements per week over the 4-week study (p<0.001 vs placebo at weeks 3 and 4). Source: Madempudi 2020.

Constipation: stool consistency
Patients reaching normal stool over 4 weeks.
0255075100People at normal stool (%)startwk 2wk 4Weeks of daily use0%24%98%

Patients reaching normal stool consistency, from 0% to 98% over 4 weeks. Source: Madempudi 2020 (Table 2).

Bacillus coagulans LactoSpore®(MTCC 5856) · in IB-PRO
Studied in gas and bloating over 4 weeks.
Gas & bloating: symptom reduction by week 4
Reduction in the GSRS indigestion subscale (gas and bloating) from baseline, LactoSpore versus placebo.
0255075100Reduction in GSRS indigestion subscale (%) by week 4LactoSpore66%Placebo10%
Overall self-rating tripled. The global patient evaluation rose from a median of 3 to 9 on a 10-point scale, versus 3 to 4 on placebo (between-group difference p<0.001).

GSRS indigestion subscale, baseline to week 4 (Majeed 2023): LactoSpore 8.91 to 3.06, placebo 9.42 to 8.43. GSRS is the validated Gastrointestinal Symptom Rating Scale; its indigestion subscale captures gas, bloating, and related upper-GI discomfort.

Individual results vary.

Our clinical evidence hub is password-protected. If your password hasn't been emailed to you, request your password here.

The products

Two products, built on clinically studied strains

We don't make dozens of products. We make two. We put real time and resources into research and development, and we only formulate with strains that clear an exceptionally high bar of published clinical evidence, dosing each strain to match its clinical studies.

MIOME IB-ONE box and capsules
IB-ONE20MGSingle strain

Supports normal bowel movements and digestive health.

Bacillus coagulans Unique IS-2™
MTCC 5260 · ATCC PTA-11748
2 billion CFU30 capsulesOnce daily

A foundational, single-strain option that supports regular bowel movements, including occasional constipation.

MIOME IB-PRO box and capsules
IB-PRO40MGDual strain

Supports normal bowel movements, and helps with occasional bloating and digestive discomfort.

Bacillus coagulans LactoSpore®
MTCC 5856
Bacillus coagulans Unique IS-2™
MTCC 5260 · ATCC PTA-11748
4 billion CFU30 capsulesOnce daily

A dual-strain option that supports regular bowel movements, including occasional constipation, paired with support for occasional bloating and gas.

Once Daily · Low FODMAP · Gluten, Dairy & Soy Free · Third-Party Tested · Shelf-Stable

Made for the clinic

Built for the clinic, not just the shelf

Most probiotics are built to sell on a shelf. MIOME is built for the recommendation you make: evidence you can cite, a routine patients keep, and support that continues the conversation after the appointment.

Evidence you can cite

Strain-specific clinical studies at the dose we use, so the recommendation rests on the science, not a high CFU number.

A routine patients keep

One capsule a day, with or without food. Simple to recommend, and easy for patients to keep up with.

Support for the conversation

Plain-language patient handouts and dosing guidance you can share, so care continues between visits.

A dedicated contact

A real team member to answer your questions and guide you through, whenever you need them.

Ways to partner

Two ways to partner, and you can do both

Pick what fits your practice, or combine them: recommend MIOME to patients who like to order online, and stock it for those who want it in hand.

No inventory

Recommend & earn

Recommend MIOME without holding any inventory. Our exclusive partnership program, for practitioners only, gives your patients and audience a 20% discount code on their first purchase, and pays you 20% commission on that first order.

  • Join in minutes
  • Get your link and discount code
  • Patients order direct
  • Carry no inventory
Clinic shelf

Stock at wholesale

Stock MIOME and dispense directly to patients at your own retail price, above MAP. Wholesale is offered to approved partners by application, with pricing and terms shared privately.

  • Set your retail price, above MAP
  • Larger margins per unit
  • Earn on every sale
  • Low minimum orders

Both paths are open to approved partners by application.

Wholesale

Apply to stock MIOME

Wholesale is offered to approved partners by application. We review every application and reply by email with your pricing and terms. Prefer not to hold stock? Recommend and earn instead. Your details stay confidential.

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We review every application and will reply by email with pricing and terms. Keep an eye on your inbox.